Article
Polymorphisms at codons 141 and 154 in the ovine prion protein gene are associated with scrapie Nor98 cases.
The Journal of general virology - 1 Jan 2005
Moum Truls, Olsaker Ingrid, Hopp Petter, Moldal Torfinn, Valheim Mette, Moum Torbjørn, Benestad Sylvie L
Abstract excerpt
Until June 2004, thirty-eight scrapie cases with unusual features, designated Nor98, have been diagnosed in Norway. This study investigated the distribution of PrP genotypes among Nor98 cases, their flock-mates and a random sample of Norwegian slaughtered sheep. The PrP genotype distribution of Nor98 cases differed markedly from that of previous cases of classical scrapie. A leucine/phenylalanine polymorphism at...
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