Article
PrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie.
Veterinary journal (London, England : 1997) - 1 Feb 2011
Papasavva-Stylianou Penelope, Windl Otto, Saunders Ginny, Mavrikiou Petroula, Toumazos Pavlos, Kakoyiannis Charalambos
Abstract excerpt
In contrast to scrapie in sheep, the genetic basis of susceptibility to scrapie in goats is not well understood. To study the association of prion protein (PrP) alleles with susceptibility to scrapie in goats in Cyprus, the coding sequence of the caprine PrP gene was determined in 717 goats, including 218 scrapie positive animals. Several novel polymorphisms were detected, such as a novel octarepeat variant and a...
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