Article
PrP gene polymorphism in sheep breeds in Slovakia and susceptibility to scrapie.
Acta virologica - 1 Jan 2006
Tkáciková L, Rolková G, Bíres J, Novák P, Kontseková E, Imrichová D, Bhide M, Hanusovská E, Mikula I, Novák M
Abstract excerpt
We analyzed the prion protein (PrP) genotype based on the codons 136, 154 and 171 and assigned to five risk groups (R1-R5) in healthy and scrapie-affected sheep in Slovakia. In healthy (asymptomatic) population, 119 Merino, 106 Improved Valachian, 117 Tsigai, and 48 Suffolk breeds were tested. Among the asymptomatic sheep, the low-risk genotypes R1 and R2 were most abundant in Suffolk (94%) and Merino (84%)...
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