Article
Prion protein gene (PRNP) polymorphisms in Xinjiang local sheep breeds in China.
Archives of virology - 1 Oct 2006
Lan Z, Wang Z L, Liu Y, Zhang X
Abstract excerpt
Amino acid polymorphisms of the prion protein (PrP) gene (PRNP), particularly those occurring at codons 136, 154, and 171 have a significant influence on scrapie pathogenesis in many sheep breeds. We isolated blood samples from 222 sheep representing the eight main local sheep breeds in the Xinjiang Autonomous Region, the territory with the most abundant local sheep breeds in China, to identify the PRNP...
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