Article
Polymorphisms of caprine PrP gene detected in Japan.
The Journal of veterinary medical science - 1 Mar 2005
Kurosaki Yasuhisa, Ishiguro Naotaka, Horiuchi Motohiro, Shinagawa Morikazu
Abstract excerpt
Polymorphism of the PrP gene is a primary factor influencing susceptibility and incubation period in natural and experimental scrapie in sheep and goats. Polymorphisms of the caprine PrP gene in Japan were examined in 118 goats. Eight allelic variants and 19 genotypes were obtained. Amino acid polymorphisms were observed at 7 codons: 102, 142, 143, 240, 127, 146 and 211 (the latter 3 are novel polymorphisms). The...
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