Article
Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease.
International journal of immunogenetics - 1 Dec 2005
Chen R-H, Chen W-C, Wang T-Y, Tsai C-H, Tsai F-J
Abstract excerpt
Graves' disease (GD) is a common, autoimmune disease involving the thyroid gland, and it has been previously suggested that pro-inflammatory cytokines are involved in the disease's pathogenesis. The aim of this study was to test whether the interleukin (IL)-6 gene promoter region, or tumour necrosis factor (TNF)-alpha or IL-8 gene 3'-untranslated region (3'-UTR) polymorphisms could provide useful genetic markers...
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