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Article

Polymorphisms of interleukin 4 receptor gene and interleukin 10 gene are not associated with Graves' disease in the UK.

Autoimmunity - 1 May 2004

Tait Karen F, Nithiyananthan Ratnasingam, Heward Joanne M, Barnett Anthony H, Franklyn Jayne A, Gough Stephen C L

Abstract excerpt

Graves' disease (GD) is an autoimmune disorder of the thyroid gland and both environmental and genetic factors contribute to disease aetiology. Cytokines, such as interleukin 4 (IL-4) and interleukin 10 (IL-10), are involved in the immune response and may be implicated in the autoimmune disease process. Associations have been reported between single nucleotide polymorphisms (SNPs) of IL-10 and the Ile50Val...

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Identifiers

PMID: 15497451
DOI: 10.1080/08916930410001666631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of interleukin 4 receptor gene and interleukin 10 gene are not associated with Graves' disease in the UK.PMID 15497451Read ↗

No association of an interleukin 4 gene promoter polymorphism with Graves' disease in the United Kingdom.Semantic proximity Read ↗

Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.Semantic proximity Read ↗

Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease.Semantic proximity Read ↗

Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves' disease.Semantic proximity Read ↗

Lack of association between the IL-13 C-1112T, G2044A polymorphisms and Graves' disease risk: evidence from a meta-analysis.Semantic proximity Read ↗

An association of interleukin-10 gene polymorphisms with Graves' disease in two Chinese populations.Semantic proximity Read ↗

Association of an IL-4 gene haplotype with Graves disease in children: experimental study and meta-analysis.Semantic proximity Read ↗

Association of polymorphic variants of IL-1β and IL-1RN genes in the development of Graves' disease in Kashmiri population (North India).Semantic proximity Read ↗

A germline single nucleotide polymorphism at the intracellular domain of the human thyrotropin receptor does not have a major effect on the development of Graves' disease.Semantic proximity Read ↗

Lack of association between interleukin-4 gene polymorphisms and autoimmune thyroid diseases amongst Taiwanese Chinese.Semantic proximity Read ↗

Interleukin-13 gene polymorphisms in patients with Graves' disease.Semantic proximity Read ↗

Association between the IL1B (-511), IL1B (+3954), IL1RN (VNTR) polymorphisms and Graves' disease risk: a meta-analysis of 11 case-control studies.Semantic proximity Read ↗

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