Article
No association of an interleukin 4 gene promoter polymorphism with Graves' disease in the United Kingdom.
The Journal of clinical endocrinology and metabolism - 1 Aug 2001
Heward J M, Nithiyananthan R, Allahabadia A, Gibson S, Franklyn J A, Gough S C
Abstract excerpt
Graves' disease (GD) is an autoimmune thyroid disease of unknown etiology, although predisposition to the development of this disease is thought to be caused by both genetic and environmental factors. Recently, an association between a promoter polymorphism of the interleukin 4 gene and GD has been reported. A C-T base change at position -590 showed modest protection against the development of GD in a United...
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