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Article

Association of G-174C polymorphism of the interleukin-6 gene promoter with Graves' ophthalmopathy.

Autoimmunity - 1 May 2004

Bednarczuk Tomasz, Kuryłowicz Alina, Hiromatsu Yuji, Kiljańskic Jacek, Telichowska Anna, Nauman Janusz

Abstract excerpt

Interleukin-6 (IL-6) may play an important role in the pathogenesis of Graves' ophthalmopathy (GO). The aim of this study was to analyze the association of IL-6 gene promoter polymorphism, at position - 174 (G --> C, termed as G-174C), which may affect IL-6 production, with the development of GO. The G-174C polymorphism was determined in 279 Polish-Caucasian patients with Graves' disease (GD), of which 108 had...

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Identifiers

PMID: 15497456
DOI: 10.1080/0891693042000193320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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