Article
Interleukin-10 secretion differentiates dendritic cells from human liver and skin.
The American journal of pathology - 1 Feb 2004
Goddard Sarah, Youster Janine, Morgan Emma, Adams David H
Abstract excerpt
Liver dendritic cells (DCs), which may orchestrate the liver's unique immunoregulatory functions, remain poorly characterized. We used a technique of overnight migration from pieces of normal human liver and skin to obtain tissue-derived DCs with minimal culture and no additional cytokine treatment. Liver and skin DCs had a monocyte-like morphology and a partially mature phenotype, expressing myeloid markers,...
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