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Article

C1q regulation of dendritic cell development from monocytes with distinct cytokine production and T cell stimulation.

Molecular immunology - 1 May 2011

Teh Boon King, Yeo Joo Guan, Chern Lai Min, Lu Jinhua

Abstract excerpt

The causative association of complement C1q deficiency with systemic lupus erythematosus (SLE), which inevitably involves the breakdown of tolerance, remains poorly explained. Its non-hepatic, macrophage and dendritic cell (DC) origin may be highly relevant. In tissues, C1q is produced by DCs and macrophages which deposits around these cells and we ask whether this pericellular form of C1q regulates DC...

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Source

Identifiers

PMID: 21429584
DOI: 10.1016/j.molimm.2011.02.006

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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