Article
HLA Class III: A susceptibility region to systemic lupus erythematosus in Tunisian population.
PloS one - 1 Jan 2018
Hachicha Hend, Mahfoudh Nadia, Fourati Hajer, Elloumi Nesrine, Marzouk Sameh, Feki Sawsan, Fakhfakh Raouia, Frikha Faten, Ayadi Abir, Maatoug Amira, Gaddour Lilia, Hakim Feiza, Bahloul Zouheir, Makni Hafedh, Masmoudi Hatem, Kammoun Arwa
Abstract excerpt
BACKGROUND AND OBJECTIVES: Short tandem repeats (STR) are usually used as informative polymorphic markers for genetic mapping and for disease susceptibility analysis. The involvement of these microsatellite markers localized in the MHC region was reported in many auto-immune diseases. In this study we analyzed for the first time eight polymorphisms of microsatellite loci at the HLA region: D6S291, D6S273, TNFa, b...
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