Article
Tumor necrosis factor receptor 2 polymorphism in systemic lupus erythematosus: no association with disease.
Human immunology - 1 Oct 2001
Lee E B, Yoo J E, Lee Y J, Choi Y J, Park K S, Song Y W
Abstract excerpt
Genetic factors and immune dysregulation play important roles in the development of systemic lupus erythematosus (SLE). Tumor necrosis factor receptor 2 (TNFR2) is suggested to be involved in the development of SLE because its genetic locus (1p36) encompasses one of the susceptible loci for SLE and its ligand (TNF) is associated with SLE. To investigate the role of TNFR2 in the pathogenesis of SLE, 139 Korean...
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