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Article

Impaired resistance to infection does not increase the virulence of Salmonella htrA live vaccines for mice.

Microbial pathogenesis - 1 Apr 1992

Strahan K, Chatfield S N, Tite J, Dougan G, Hormaeche C E

Abstract excerpt

We have described a new class of live attenuated salmonella vaccines harbouring lesions in htrA, a stress protein gene previously. The virulence and invasiveness of Salmonella htrA mutants was investigated in three models of increased susceptibility to Salmonella infection. These included BALB/c mice, either given sublethal whole body irradiation (350 R) or administered rabbit anti-TNF alpha antiserum, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1630300
DOI: 10.1016/0882-4010(92)90049-t

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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