Article
Salmonella enterica serovar typhimurium surA mutants are attenuated and effective live oral vaccines.
Infection and immunity - 1 Mar 2000
Sydenham M, Douce G, Bowe F, Ahmed S, Chatfield S, Dougan G
Abstract excerpt
A previously described attenuated TnphoA mutant (BRD441) of Salmonella enterica serovar Typhimurium C5 (I. Miller, D. Maskell, C. Hormaeche, K. Johnson, D. Pickard, and G. Dougan, Infect. Immun. 57:2758-2763, 1989) was characterized, and the transposon was shown to be inserted in surA, a gene which encodes a peptidylprolyl-cis, trans-isomerase. A defined surA deletion mutation was introduced into S. enterica...
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