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Article

A stepwise framework for the normalization of array CGH data.

BMC bioinformatics - 18 Nov 2005

Khojasteh Mehrnoush, Lam Wan L, Ward Rabab K, MacAulay Calum

Abstract excerpt

BACKGROUND: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly used to infer the relative amounts of the test and reference sample DNA levels. This ratio may be influenced by systematic measurement effects from non-biological sources that can introduce biases in the estimated ratios. These biases...

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Identifiers

PMID: 16297240
DOI: 10.1186/1471-2105-6-274
PMCID: PMC1310623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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