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Article

PAIR: paired allelic log-intensity-ratio-based normalization method for SNP-CGH arrays.

Bioinformatics (Oxford, England) - 1 Feb 2013

Yang Shengping, Pounds Stanley, Zhang Kun, Fang Zhide

Abstract excerpt

MOTIVATION: Normalization is critical in DNA copy number analysis. We propose a new method to correctly identify two-copy probes from the genome to obtain representative references for normalization in single nucleotide polymorphism arrays. The method is based on a two-state Hidden Markov Model. Unlike most currently available methods in the literature, the proposed method does not need to assume that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23196989
DOI: 10.1093/bioinformatics/bts683
PMCID: PMC3562063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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