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Article

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios.

BMC bioinformatics - 2 Oct 2008

Staaf Johan, Vallon-Christersson Johan, Lindgren David, Juliusson Gunnar, Rosenquist Richard, Höglund Mattias, Borg Ake, Ringnér Markus

Abstract excerpt

BACKGROUND: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). Methods developed for normalization of WGG arrays have mostly focused on...

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PMID: 18831757
DOI: 10.1186/1471-2105-9-409
PMCID: PMC2572624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18831757-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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