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Article

Group normalization for genomic data.

PloS one - 1 Jan 2012

Ghandi Mahmoud, Beer Michael A

Abstract excerpt

Data normalization is a crucial preliminary step in analyzing genomic datasets. The goal of normalization is to remove global variation to make readings across different experiments comparable. In addition, most genomic loci have non-uniform sensitivity to any given assay because of variation in local sequence properties. In microarray experiments, this non-uniform sensitivity is due to different DNA...

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PMID: 22912661
DOI: 10.1371/journal.pone.0038695
PMCID: PMC3418286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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