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Article

Normalization of array-CGH data: influence of copy number imbalances.

BMC genomics - 22 Oct 2007

Staaf Johan, Jönsson Göran, Ringnér Markus, Vallon-Christersson Johan

Abstract excerpt

BACKGROUND: High-resolution microarray-based comparative genomic hybridization (CGH) techniques have successfully been applied to study copy number imbalances in a number of settings such as the analysis of cancer genomes. For normalization of array-CGH data, methods initially developed for gene expression microarray analysis have, in general, been directly adopted and used. However, these methods are designed to...

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Identifiers

PMID: 17953745
DOI: 10.1186/1471-2164-8-382
PMCID: PMC2190775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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