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Article

Single-cell copy number variation detection.

Genome biology - 29 Aug 2011

Cheng Jiqiu, Vanneste Evelyne, Konings Peter, Voet Thierry, Vermeesch Joris R, Moreau Yves

Abstract excerpt

Detection of chromosomal aberrations from a single cell by array comparative genomic hybridization (single-cell array CGH), instead of from a population of cells, is an emerging technique. However, such detection is challenging because of the genome artifacts and the DNA amplification process inherent to the single cell approach. Current normalization algorithms result in inaccurate aberration detection for...

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Identifiers

PMID: 21854607
DOI: 10.1186/gb-2011-12-8-r80
PMCID: PMC3245619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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