Article
Pathogenesis of IgA nephropathy.
Seminars in nephrology - 1 Nov 2003
Wada Jun, Sugiyama Hitoshi, Makino Hirofumi
Abstract excerpt
Immunoglobulin A (IgA) nephropathy is an immune-complex-mediated glomerulonephritis characterized by the presence of immunoglobulin A deposits in mesangial and paramesangial regions. The patients with IgA nephropathy present with varying clinical symptoms (eg, microhematuria with preserved renal function or progressive deterioration of renal functions resulting in end-stage renal disease). The factors involved in...
Topics
- Animals
- Biopsy, Needle
- Cytokines
- Genetic Markers
- Genetic Predisposition to Disease
- Glomerulonephritis, IGA
- Humans
- Immunohistochemistry
- Renin-Angiotensin System
- Risk Factors
- Sensitivity and Specificity