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Article

Interferon-alpha2a is sufficient for promoting dendritic cell immunogenicity.

Clinical and experimental immunology - 1 Dec 2005

Tamir A, Jordan W J, Ritter M, Habib N, Lechler R I, Foster G R, Lombardi G

Abstract excerpt

Type I interferons (IFNs) are widely used therapeutically. IFN-alpha2a in particular is used as an antiviral agent, but its immunomodulatory properties are poorly understood. Dendritic cells (DCs) are the only antigen-presenting cells able to prime naive T cells and therefore play a crucial role in initiating the adaptive phase of the immune response. We studied the effects of IFN-alpha2a on DC maturation and its...

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Identifiers

PMID: 16297159
DOI: 10.1111/j.1365-2249.2005.02933.x
PMCID: PMC1809533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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