Article

Maturation signatures of conventional dendritic cell subtypes in COVID-19 reflect direct viral sensing

2021-03-03

Abstract excerpt

Growing evidence suggests that conventional dendritic cells (cDCs) undergo aberrant maturation in COVID-19 and this negatively affects T cell activation. The presence of functional effector T cells in mild patients and dysfunctional T cells in severely ill patients suggests that adequate T cell responses are needed to limit disease severity. Therefore, understanding how cDCs cope with SARS-CoV-2 infections can hel...

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Literature Corpus work: 2a4af830-c906-5031-90d4-c798267c2bca
DOI: 10.1101/2021.03.03.433597

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