Article
Dendritic cell maturation with poly(I:C)-based versus PGE2-based cytokine combinations results in differential functional characteristics relevant to clinical application.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jun 2008
Möller Ines, Michel Kathrin, Frech Nathalie, Burger Meike, Pfeifer Dietmar, Frommolt Peter, Veelken Hendrik, Thomas-Kaskel Anna-K
Abstract excerpt
In vitro maturation of dendritic cells (DCs) for cancer immunotherapy may be accomplished by cytokine cocktails containing prostaglandin E2 (PGE2). More recently, a poly(I:C)-based protocol has been proposed as a potentially superior alternative because of a strong induction of interleukin (IL)-1...
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