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Article

ALOX5 promoter genotype and response to montelukast in moderate persistent asthma.

Respiratory medicine - 1 Jun 2008

Telleria Juan J, Blanco-Quiros Alfredo, Varillas David, Armentia Alicia, Fernandez-Carvajal Isabel, Jesus Alonso M, Diez Ignacio

Abstract excerpt

BACKGROUND: It was hypothesized that asthmatic patients with mutant alleles in the leukotriene pathway should not respond to leukotriene receptor antagonists and the concept of a tailored treatment is increasingly supported. METHODS: Sixty-one patients (mean age 24.9 years, range 14-52) with mode...

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Source

Identifiers

PMID: 18339529
DOI: 10.1016/j.rmed.2008.01.011

Genes

ALOX5
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18339529-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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ALOX5 promoter genotype and response to montelukast in moderate persistent asthma.PMID 18339529Read ↗

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Influence of leukotriene pathway polymorphisms on response to montelukast in asthma.Semantic proximity Read ↗

Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population.Semantic proximity Read ↗

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