Genetic analysis of the merozoite surface protein-1 block 2 allelic types in Plasmodium falciparum clinical isolates from Lao PDR.

doi:10.1186/1475-2875-10-371

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Article

Genetic analysis of the merozoite surface protein-1 block 2 allelic types in Plasmodium falciparum clinical isolates from Lao PDR.

Malaria journal - 17 Dec 2011

Khaminsou Naly, Kritpetcharat Onanong, Daduang Jureerut, Charerntanyarak Lertchai, Kritpetcharat Panutas

Abstract excerpt

BACKGROUND: MSP-1 is one of the potential malarial vaccine candidate antigens. However, extensive genetic polymorphism of this antigen in the field isolates of Plasmodium falciparum represents a major hindrance for the development of an effective vaccine. Therefore, this study aimed to establish the prevalence and genetic polymorphisms of K1, MAD20 and RO33 allelic types of msp-1 block 2 among P. falciparum...

Topics

Adolescent
Adult
Aged
Alleles
Base Sequence
Child
Child, Preschool
DNA, Protozoan
Evolution, Molecular
Female
Humans
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Laos

Malaria, Falciparum

Male

Merozoite Surface Protein 1

Middle Aged

Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 22177111
DOI: 10.1186/1475-2875-10-371
PMCID: PMC3281801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22177111-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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