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Article

Genetic analysis of the merozoite surface protein-1 block 2 allelic types in Plasmodium falciparum clinical isolates from Lao PDR.

Malaria journal - 17 Dec 2011

Khaminsou Naly, Kritpetcharat Onanong, Daduang Jureerut, Charerntanyarak Lertchai, Kritpetcharat Panutas

Abstract excerpt

BACKGROUND: MSP-1 is one of the potential malarial vaccine candidate antigens. However, extensive genetic polymorphism of this antigen in the field isolates of Plasmodium falciparum represents a major hindrance for the development of an effective vaccine. Therefore, this study aimed to establish the prevalence and genetic polymorphisms of K1, MAD20 and RO33 allelic types of msp-1 block 2 among P. falciparum...

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Identifiers

PMID: 22177111
DOI: 10.1186/1475-2875-10-371
PMCID: PMC3281801

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