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Article

Genetic diversity in the merozoite surface protein 1 gene of Plasmodium falciparum in different malaria-endemic localities.

The American journal of tropical medicine and hygiene - 1 Sept 2004

Raj Dipak Kumar, Das Bibhu Ranjan, Dash A P, Supakar Prakash C

Abstract excerpt

A number of stage-specific antigens have been characterized for vaccine development in Plasmodium falciparum malaria. The polymorphic merozoite surface protein 1 (MSP-1) of Plasmodium falciparum is a major asexual blood stage malaria vaccine candidate antigen. In the present study, we analyzed the impact of hyperendemic malaria transmission, mesoendemic malaria transmission, and multiple infection on allelic...

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PMID: 15381807

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