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Article

Activation defects caused by mutations in Escherichia coli rpoA are promoter specific.

Journal of bacteriology - 1 Aug 1992

Gussin G N, Olson C, Igarashi K, Ishihama A

Abstract excerpt

Escherichia coli RNA polymerases containing mutated alpha subunits were tested for their ability to respond to three different positive regulators (activators) in vitro. The two alpha (rpoA) mutants, alpha-256 and alpha-235, have deletions of the C-terminal 73 and 94 amino acids, respectively. In runoff transcription assays catalyzed by reconstituted holoenzyme, the effects of the mutations on each of three...

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Identifiers

PMID: 1629175
DOI: 10.1128/jb.174.15.5156-5160.1992
PMCID: PMC206338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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