Article
Involvement of the Escherichia coli RNA polymerase alpha subunit in transcriptional activation by the bacteriophage lambda CI and CII proteins.
Gene - 1 Dec 1992
Wegrzyn G, Glass R E, Thomas M S
Abstract excerpt
Escherichia coli cells harbouring the rpoA341 mutation produce an RNA polymerase which transcribes inefficiently certain operons subject to positive control. Here, we demonstrate that the rpoA341 allele also prevents lysogenization of the host strain by bacteriophage lambda, a process dependent upon the action of two phage-encoded activators. This phenomenon was shown to arise from an inability to establish an...
Topics
- Bacteriophage lambda
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Escherichia coli
- Lysogeny
- Mutation
- Promoter Regions, Genetic
- Repressor Proteins
- Transcription Factors
- Transcription, Genetic
- Viral Proteins