Article
N- and C-terminal regions of the quorum-sensing activator TraR cooperate in interactions with the alpha and sigma-70 components of RNA polymerase.
Molecular microbiology - 1 Oct 2009
Qin Yinping, Keenan Carrie, Farrand Stephen K
Abstract excerpt
Positive control (PC) mutants defining 20 residues of the quorum-sensing activator TraR were isolated that bind DNA but show defects in activating transcription from class I, class II or both types of promoters. These PC residues, located in both the N- and C-terminal regions, combine to form three patches, one on the top (II) and two near the DNA binding domain on both lateral faces of the dimer (I and III)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.