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Article

MC4R oligomerizes independently of extracellular cysteine residues.

Peptides - 1 Feb 2006

Elsner Andrea, Tarnow Patrick, Schaefer Michael, Ambrugger Petra, Krude Heiko, Grüters Annette, Biebermann Heike

Abstract excerpt

The melanocortin 4 receptor (MC4R) plays an essential role in weight regulation. Recently we could show that the MC4R is able to form receptor dimers. In the present study we investigated the role of extracellular cysteine residues and the structure of the third extracellular loop for receptor dimerization. None of the four extracellular cysteine residues nor the structure of the third extracellular loop play a...

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Source

Identifiers

PMID: 16289450
DOI: 10.1016/j.peptides.2005.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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