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Article

Structural insight into the role of the human melanocortin 3 receptor cysteine residues on receptor function.

Peptides - 1 Dec 2011

Yang Yingkui, Chen Min, McPherson David, Mishra Vinod, Harmon Carroll M

Abstract excerpt

Melanocortin-3 receptor (MC3R), expressed in the hypothalamus and limbic systems of the brain, as well as by peripheral sites, plays an important role in the regulation of energy homeostasis and other physiological functions. Past work shows that MC3R-deficiency resulted in fat mass increase, feeding efficiency increase, hyperleptinemia and mild hyperinsulinemia in mice and human. MC3R belongs to G-protein...

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Identifiers

PMID: 22079958
DOI: 10.1016/j.peptides.2011.09.024
PMCID: PMC3242444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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