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Article

Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract.

Oncogene - 30 Mar 2006

Mongiat-Artus P, Miquel C, Van der Aa M, Buhard O, Hamelin R, Soliman H, Bangma C, Janin A, Teillac P, van der Kwast T, Praz F

Abstract excerpt

A subset of upper urinary tract urothelial cell carcinomas (UUC), arising sporadically or as a manifestation of hereditary non-polyposis colorectal cancer, displays microsatellite instability (MSI). MSI tumours are characterized by defective mismatch repair and accumulation of frameshift mutations in numerous genes harbouring repeats in their coding sequences. We have evaluated the incidence of MSI in UUC and the...

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Source

Identifiers

PMID: 16288216
DOI: 10.1038/sj.onc.1209229

Genes

MRE11
BAX
MSH6
RAD50
ATR
BLM
MBD4
MLH1
MSH2
MSH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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