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Article

Microsatellite Instability Analysis (MSA) for Bladder Cancer: Past History and Future Directions

28 Nov 2021

Abstract excerpt

Microsatellite instability (MSI), the spontaneous loss or gain of nucleotides from repetitive DNA tracts, is a diagnostic phenotype for gastrointestinal, endometrial, colorectal, and bladder cancers; yet a landscape of instability events across a wider variety of cancer types is beginning to be discovered. The epigenetic inactivation of the MLH1 gene is often associated with sporadic MSI cancers. Recent...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 34884669
DOI: 10.3390/ijms222312864

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