Article
Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability.
Cancer research - 15 Jul 2002
Vassileva Vessela, Millar Anna, Briollais Laurent, Chapman William, Bapat Bharati
Abstract excerpt
Microsatellite instability (MSI) is observed in a subset of endometrial cancers (ECs) and is attributed to defects in mismatch repair. Mismatch repair deficiency allows for accumulation of mutations in the coding repeats of key target genes, which may be involved in the initiation and progression...
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