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Article

Microsatellite instability and TARBP2 mutation study in upper urinary tract urothelial carcinoma.

American journal of clinical pathology - 1 Jun 2013

Bai Shuting, Nunez Amberly L, Wei Shi, Ziober Amy, Yao Yuan, Tomaszewski John E, Bing Zhanyong

Abstract excerpt

Microsatellite instability (MSI) contributes to the tumorigenesis of upper urinary tract urothelial carcinomas (UUT-UCs). In this study, we first used MLH1 and MSH2 immunohistochemistry to identify patients with loss of expression of either or both of these proteins in 132 UUT-UCs. We found a total loss of MSH2 expression in 4 patients. MSI was evaluated using 5 markers in these 4 cases. All of the tumors had...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23690119
DOI: 10.1309/AJCPBSLP8XHSWLOW

Genes

MSH2
TARBP2
DICER1
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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