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Article

In vivo formation of unstable heterokaryons after liver damage and hematopoietic stem cell/progenitor transplantation.

Stem cells (Dayton, Ohio) - 1 Apr 2006

Kashofer Karl, Siapati Elena K, Bonnet Dominique

Abstract excerpt

Following reports of lineage plasticity in human hematopoietic stem cells (HSCs), we investigated the potential of human cord blood HSC-enriched cells to create hepatocytes in hosts after inducing liver damage. Carbon tetrachloride induces severe liver damage and subsequent repair via mitosis of resident hepatocytes. It additionally leads to a threefold increase in homing of human mononuclear cells to bone marrow...

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Identifiers

PMID: 16282440
DOI: 10.1634/stemcells.2005-0405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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