Article
Isolation and characterization of adult human liver progenitors from ischemic liver tissue derived from therapeutic hepatectomies.
Tissue engineering. Part A - 1 Jul 2009
Stachelscheid Harald, Urbaniak Thomas, Ring Alexander, Spengler Berlind, Gerlach Jörg C, Zeilinger Katrin
Abstract excerpt
Recent evidence suggests that progenitor cells in adult tissues and embryonic stem cells share a high resistance to hypoxia and ischemic stress. To study the ischemic resistance of adult liver progenitors, we characterized remaining viable cells in human liver tissue after cold ischemic treatment for 24-168 h, applied to the tissue before cell isolation. In vitro cultures of isolated cells showed a rapid decline...
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