Article
In vitro cultured islet-derived progenitor cells of human origin express human albumin in severe combined immunodeficiency mouse liver in vivo.
Stem cells (Dayton, Ohio) - 1 Jan 2004
von Mach Marc-Alexander, Hengstler Jan Georg, Brulport Marc, Eberhardt Michael, Schormann Wiebke, Hermes Matthias, Prawitt Dirk, Zabel Bernhard, Grosche Jens, Reichenbach Andreas, Müller Beat, Weilemann Ludwig Sacha, Zulewski Henryk
Abstract excerpt
Studies in rodents suggest the presence of a hepatopancreatic stem cell in adult pancreas that may give rise to liver cells in vivo. The aim of the present study was to determine the ability of human islet-derived cells to adopt a hepatic phenotype in vivo. Cultured human islet-derived progenitor cells that did not express albumin in vitro were stained with the red fluorescent dye PKH26 and injected into the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
