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Article

A splicing repressor domain in polypyrimidine tract-binding protein.

The Journal of biological chemistry - 13 Jan 2006

Robinson Fiona, Smith Christopher W J

Abstract excerpt

Polypyrimidine tract-binding protein (PTB) is an hnRNP with four RRM type domains. It plays roles as a repressive alternative splicing regulator of multilple target genes, as well as being involved in pre-mRNA 3' end processing, mRNA localization, stability, and internal ribosome entry site-mediated translation. Here we have used a tethered function assay, in which a fusion protein of PTB and the bacteriophage...

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Identifiers

PMID: 16282332
DOI: 10.1074/jbc.M510578200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A splicing repressor domain in polypyrimidine tract-binding protein.PMID 16282332Read ↗

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