Article
Chemical shift mapping of RNA interactions with the polypyrimidine tract binding protein.
Nucleic acids research - 15 Jan 2002
Yuan Xuemei, Davydova Natalia, Conte Maria R, Curry Stephen, Matthews Stephen
Abstract excerpt
The polypyrimidine tract binding protein (PTB), a homodimer that contains four RRM-type RNA binding domains per monomer, plays important roles in both the regulation of alternative splicing and the stimulation of translation initiation as directed by the internal ribosome entry sites of certain picornaviruses. We have used chemical shift mapping experiments to probe the interactions between PTB-34, a recombinant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
