Article
Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2.
RNA (New York, N.Y.) - 1 Feb 2012
Sun Shuying, Zhang Zuo, Fregoso Oliver, Krainer Adrian R
Abstract excerpt
RBFOX1 and RBFOX2 are alternative splicing factors that are predominantly expressed in the brain and skeletal muscle. They specifically bind the RNA element UGCAUG, and regulate alternative splicing positively or negatively in a position-dependent manner. The molecular basis for the position dependence of these and other splicing factors on alternative splicing of their targets is not known. We explored the...
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