Article
Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo.
RNA (New York, N.Y.) - 1 Jul 1997
Pérez I, Lin C H, McAfee J G, Patton J G
Abstract excerpt
Alternative splicing of pre-mRNA is a commonly used mechanism to regulate gene expression in higher eukaryotes. However, with the exception of regulated cascades in Drosophila, the cis-acting elements and the trans-acting factors that control tissue- and/or developmentally regulated splicing remain largely unidentified. Cis-acting elements that control smooth muscle-specific repression of exon 3 of...
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