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Article

The domains of polypyrimidine tract binding protein have distinct RNA structural preferences.

Biochemistry - 17 Mar 2009

Clerte Caroline, Hall Kathleen B

Abstract excerpt

PTB (polypyrimidine tract binding protein) participates in cellular regulatory functions in the nucleus and the cytoplasm. It binds to internal ribosome entry sites to facilitate their use in cap-independent translation. It binds to polypyrimidine tracts in pre-mRNA introns to repress inclusion of exons. It binds to the 3' untranslated regions of mRNAs to stabilize the message. These RNAs have various structures,...

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Identifiers

PMID: 19226116
DOI: 10.1021/bi8016872
PMCID: PMC2766422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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