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Article

CYP17 gene polymorphism in relation to breast cancer risk: a case-control study.

Breast cancer research : BCR - 1 Jan 2005

Einarsdóttir Kristjana, Rylander-Rudqvist Tove, Humphreys Keith, Ahlberg Susanne, Jonasdottir Gudrun, Weiderpass Elisabete, Chia Kee Seng, Ingelman-Sundberg Magnus, Persson Ingemar, Liu Jianjun, Hall Per, Wedrén Sara

Abstract excerpt

INTRODUCTION: The c.1-34T>C 5' promoter region polymorphism in cytochrome P450c17 (CYP17), a key enzyme in the biosynthesis of estrogen, has been associated with breast cancer risk, but most previous studies have been relatively small. METHODS: We genotyped 1,544 incident cases of primary breast cancer and 1,502 population controls, all postmenopausal Swedish women, for the CYP17 c.1-34T>C polymorphism and...

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Identifiers

PMID: 16280037
DOI: 10.1186/bcr1319
PMCID: PMC1410739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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