Article
CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study.
Breast cancer research : BCR - 1 Jan 2005
Chang Jiun-Horng, Gertig Dorota M, Chen Xiaoqing, Dite Gillian S, Jenkins Mark A, Milne Roger L, Southey Melissa C, McCredie Margaret R E, Giles Graham G, Chenevix-Trench Georgia, Hopper John L, Spurdle Amanda B
Abstract excerpt
INTRODUCTION: Because CYP17 can influence the degree of exposure of breast tissues to oestrogen, the interaction between polymorphisms in this gene and hormonal risk factors is of particular interest. We attempted to replicate the findings of studies assessing such interactions with the -34T-->C polymorphism. METHODS: Risk factor and CYP17 genotyping data were derived from a large Australian population-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.