Article
CYP17 5'-UTR MspA1 polymorphism and the risk of premenopausal breast cancer in a German population-based case-control study.
Breast cancer research : BCR - 1 Jan 2005
Verla-Tebit Emaculate, Wang-Gohrke Shan, Chang-Claude Jenny
Abstract excerpt
INTRODUCTION: Studies on the association between the cytochrome P450c17alpha gene (CYP17) 5'-untranslated region MspA1 genetic polymorphism and breast cancer risk have yielded inconsistent results. Higher levels of estrogen have been reported among young nulliparous women with the A2 allele. Therefore we assessed the impact of CYP17 genotypes on the risk of premenopausal breast cancer, with emphasis on parity....
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