Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.

doi:10.1002/ana.20673

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Article

Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.

Annals of neurology - 1 Jan 2006

Smemo Scott, Nowotny Petra, Hinrichs Anthony L, Kauwe John S K, Cherny Sara, Erickson Katherine, Myers Amanda J, Kaleem Mona, Marlowe Lauren, Gibson Alison M, Hollingworth Paul, O'Donovan Michael C, Morris Chris M, Holmans Peter, Lovestone Simon, Morris John C, Thal Leon, Li Yonghong, Grupe Andrew, Hardy John, Owen Michael J, Williams Julie, Goate Alison

Abstract excerpt

Several studies have reported evidence for linkage of late-onset Alzheimer's disease (LOAD) to chromosome 9. Recently, an intronic polymorphism affecting alternative splicing of exon 8 of ubiquilin 1 (UBQLN1) was reported to be associated with LOAD. We attempted to replicate this observation by genotyping this polymorphism, rs12344615 (also known as UBQ-8i), in a large sample of 1,544 LOAD cases and 1,642...

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Identifiers

PMID: 16278862
DOI: 10.1002/ana.20673

Genes

UBQLN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.PMID 16278862Read ↗

Lack of association of two chromosome 10q24 SNPs with Alzheimer's disease.Semantic proximity Read ↗

The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.Semantic proximity Read ↗

Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series.Semantic proximity Read ↗

Lack of association between UBQLN1 and Alzheimer disease.Semantic proximity Read ↗

Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures.Semantic proximity Read ↗

No association between SNP rs498055 on chromosome 10 and late-onset Alzheimer disease in multiple datasets.Semantic proximity Read ↗

No association of SORL1 SNPs with Alzheimer's disease.Semantic proximity Read ↗

Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.Semantic proximity Read ↗

Replication study of genome-wide associated SNPs with late-onset Alzheimer's disease.Semantic proximity Read ↗

Presenilin-1 intron 8 polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.Semantic proximity Read ↗

Family-based association between Alzheimer's disease and variants in UBQLN1.Semantic proximity Read ↗

Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.Semantic proximity Read ↗

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