Article
Genetic association of ubiquilin with Alzheimer's disease and related quantitative measures.
Molecular psychiatry - 1 Mar 2006
Kamboh M I, Minster R L, Feingold E, DeKosky S T
Abstract excerpt
The gene coding for ubiquilin 1 (UBQLN1) is located near a linkage peak on chromosome 9q22.2 and it also impacts the function of presenilin proteins involved in early-onset Alzheimer's disease (AD). Recently, genetic variation in UBQLN1 has been shown to affect the risk of AD in two independent family-based samples. The purpose of this study was to confirm the reported association in a large case-control sample...
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